Basic Information
VIS ID
TVIS30014686
Fusion event
HIV-chr10 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
64448314/62688554 (Hg38)
End
64448404/62688554 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA10C
Nearest miRNA
hsa-mir-1265/Upstream/5383995; hsa-mir-107/Downstream/684403;
Nearest TSS
ENST00000439456/Upstream/44683; ENST00000373783/Downstream/116303;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/313893, chr10-CpG: 152/Downstream/116121
Nearby gene
ZNF365(No orient, 16543)
Upstream sequence
tttgcagtgagccacgattgcaccattgcactccagcccaggtgacagtgtgagactctgtctcaaaaaaatatatatatatagtttgcagagtcccagg
Downstream sequence
ACTTGAGAAATATCAGATTGCTAGGTTATTTTCTGAACAAGACACCACAAAATATAAAAACTCTTTCAGATAATGGAGTACAGACTAGAAATATTAAACT
Target sequence
atcacacaacaaagaaagcagagaagggtggatttggagctggaaaccaataacttagtaactgacaTGAGGACTTTTACATAGCACATG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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