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VISDB
Viral Integration Site DataBase
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TVIS30014687
Basic Information
VIS ID
TVIS30014687
Fusion event
HIV-JMJD1C integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
64996206/63236446 (Hg38)
End
64996381/63236446 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10C
Target gene
JMJD1C
miRNAs that regulate target gene
hsa-mir-326
;
hsa-let-7e-5p
;
hsa-mir-374a-5p
;
hsa-mir-718
;
hsa-mir-587
;
hsa-mir-6084
;
hsa-mir-5581-5p
;
hsa-mir-4297
;
hsa-mir-145-3p
;
hsa-mir-6880-3p
;
hsa-mir-4485-5p
;
hsa-mir-2681-5p
;
hsa-mir-5579-3p
;
hsa-mir-889-3p
;
hsa-mir-208b-5p
;
hsa-mir-208a-5p
;
hsa-mir-590-3p
;
hsa-mir-513c-3p
;
hsa-mir-513a-3p
;
hsa-mir-3606-3p
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-548n
;
hsa-mir-23c
;
hsa-mir-130a-5p
;
hsa-mir-23a-3p
;
hsa-mir-23b-3p
;
hsa-mir-8081
;
hsa-mir-627-5p
;
hsa-mir-937-5p
;
hsa-mir-627-3p
;
hsa-mir-205-5p
;
hsa-mir-6500-3p
;
hsa-mir-3614-5p
;
hsa-mir-6875-3p
;
hsa-mir-670-3p
;
hsa-mir-4762-5p
;
hsa-mir-513b-3p
;
hsa-mir-3662
Nearest miRNA
hsa-mir-1265/Upstream/5931887; hsa-mir-107/Downstream/136511;
Nearest TSS
ENST00000439456/Upstream/18735;
ENST00000609436/Downstream/32429;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/102870
,
chr10-CpG: 122/Downstream/228664
Upstream sequence
ACCAGAGTAAAAAAATCAGATAAATTAAGAAAACATTATAAAACCACTTGAAGAAAAATGTGTTTTCTTCTAAAGCCACATGTTAATATTCTTTGTGATA
Downstream sequence
ACTTAAACTGAAACAAACTCAGGAAGGCCTGGGAACTGTTTAATATTTTCCAAAGTAGTAACTGAAAATATTCCTCCAGCACAACCCAAGCTTTAAGAAG
Target sequence
CTTTTAATAATAGTTTTGAACTTTTTATGGCAGTTCAAAAGTCTGGAAGGCAGTTTTTCTTTCAAGCTATTTATTGGCATGACTTTTACACAGTTGAGTCATCATGAGTTTAACCTACTGAGTCACCTGCTTACAGCATCTGCCAACCACAATTTACTAACTGCAGCTTCCTCAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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