Basic Information
VIS ID
TVIS30014694
Fusion event
HIV-P4HA1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
74813921/73054163 (Hg38)
End
74813606/73054163 (Hg38)
Orient
-
Location type
Intronic
Target gene
P4HA1
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-335-5p ; hsa-mir-941 ; hsa-mir-877-3p ; hsa-mir-320a ; hsa-mir-145-5p ; hsa-mir-30e-5p
Nearest miRNA
hsa-mir-1265/Upstream/333063; hsa-mir-107/Downstream/2498295;
Nearest TSS
ENST00000439456/Upstream/37302; ENST00000431293/Downstream/17132;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/361324, chr10-CpG: 103/Downstream/41937
Upstream sequence
gtgccaccatgcccagctaattttgtatttttagtagagatggagttgatcaggctggtctcgaactcctgatctcaggtgatccacccgccttggcctc
Downstream sequence
ccaaggtgctgggattacaggcataagccaccgcgcccggccACCATATGAGATATATCTATCTCATCCCTAACCAACAATCTGGGCAAGAGATGAATGT
Target sequence
ATGAAACATCCATTAAGTTGAAATATACTATTTCCTAACAGTAGGAATTACCATATGAGATACATCTCtttttttttttttcttttgagacagagtcttgctctgttgcccaggctggaatgcaatggcacaatctcagctcaccacaacctccgcctcccaggttcaagtgattctcctgtctcagcctcctgagtagctgggattataggcatgtgccaccatgcccagctaattttgtatttttagtagaga
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate