Basic Information
VIS ID
TVIS30014696
Fusion event
HIV-chr10 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.2
Reference genome
GRCh37/hg19
Start
75193587/73433829 (Hg38)
End
75193521/73433829 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1265/Upstream/712729; hsa-mir-107/Downstream/2118629;
Nearest TSS
ENST00000439456/Upstream/268; ENST00000595595/Downstream/33790;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/19637, chr10-CpG: 45/Downstream/61446
Nearby gene
MSS51(-268) ; PPP3CB(+2599) ;
Upstream sequence
CCTGCCTGAGGGCTTCTCTCTAACCTTTGTTCTCTGCCAAGGGGGCTCAGGACTGTCAACACTCCCAAGTGTTAGCCAAGTAAAGGCCAGGCAGGCTGAC
Downstream sequence
AAAAAATGAAACCTGCTGCTTCCTAGACTTCTCTCACTCAAGGCAATATTTCTGTTCTCAGTTTACAGCTTCAGAAGAAAACCCTTTGGATTAGTGCAGA
Target sequence
TGCCAAGGGGGCTCAGGACTGTCAACACTCCCAAGTGTTAGCCAAGTAAAGGCCAGGCAGGCTGAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate