Basic Information
VIS ID
TVIS30014699
Fusion event
HIV-chr10 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
80823541/79063784 (Hg38)
End
80823953/79063784 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Nearest miRNA
hsa-mir-1265/Upstream/3511231; hsa-mir-107/Downstream/7200910;
Nearest TSS
ENST00000439456/Upstream/59981; ENST00000472035/Downstream/3684;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/89528, chr10-CpG: 270/Downstream/3223
Nearby gene
ZMIZ1(+5210) ;
Upstream sequence
GGCCGCCCTCAAACTCTAAAGTGAACTGTAGCTCAGTCCAAGGGTTAAAGGCTCAGACCTacagaatcttaggacaatcagaggcaaaagtgctggtgga
Downstream sequence
AGAGCTGGGCAGGGCCCAAATGCTTCCTGTATCCACCAAGGGGTGAACTCTAAATGTAATCTCCATTACCTCACTGCCATGGGAGGCACCCTGGTCATTC
Target sequence
tatcccacactctctcacttggcagatggggaacaggcacagggagagtttgtgatgtgctcaggccacacagcaagtcaggcaatggcgggctgggcacataggtgtcccggctcctgaggcaggctcccagcctattctctTGTGACTCCCATCTGAAGAAGGGGTTGGTGGTTGAACTGGGTCTCGAACCATAGGGCAGAACTCCATGGTAGAAAGTGAGAAGACGGCTGGCTTGAGGGAAGGACATTGGAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate