Basic Information
VIS ID
TVIS30014700
Fusion event
HIV-chr10 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
80823546/79063789 (Hg38)
End
80823409/79063789 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D
Nearest miRNA
hsa-mir-1265/Upstream/3511236; hsa-mir-107/Downstream/7200905;
Nearest TSS
ENST00000439456/Upstream/59986; ENST00000472035/Downstream/3679;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/89533, chr10-CpG: 270/Downstream/3218
Nearby gene
ZMIZ1(+5205) ;
Upstream sequence
CCCTCAAACTCTAAAGTGAACTGTAGCTCAGTCCAAGGGTTAAAGGCTCAGACCTacagaatcttaggacaatcagaggcaaaagtgctggtggatatcc
Downstream sequence
cacactctctcacttggcagatggggaacaggcacagggagagtttgtgatgtgctcaggccacacagcaagtcaggcaatggcgggctgggcacatagg
Target sequence
ATGGCCCCCTCTGAAAGCCCTCCCTAAAGCAGGGCCGCCCTCAAACTCTAAAGTGAACTGTAGCTCAGTCCAAGGGTTAAAGGCTCAGACCTacagaatcttaggacaatcagaggcaaaagtgctggtggatatcc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate