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TVIS30014704
Basic Information
VIS ID
TVIS30014704
Fusion event
HIV-ARMH3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
103680991/101921234 (Hg38)
End
103680708/101921234 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10D
;
FRA10A
;
FRA10B
Target gene
ARMH3
miRNAs that regulate target gene
hsa-mir-6745
;
hsa-mir-363-5p
;
hsa-mir-555
;
hsa-mir-608
;
hsa-mir-4651
;
hsa-mir-7110-5p
;
hsa-mir-6842-5p
;
hsa-mir-6752-5p
;
hsa-mir-761
;
hsa-mir-3619-5p
;
hsa-mir-214-3p
;
hsa-mir-6510-5p
;
hsa-mir-6732-5p
;
hsa-mir-3936
;
hsa-mir-4520-3p
;
hsa-mir-6721-5p
;
hsa-mir-6860
;
hsa-mir-5189-5p
;
hsa-mir-612
;
hsa-mir-3187-5p
;
hsa-mir-1285-3p
;
hsa-mir-4638-3p
;
hsa-mir-922
;
hsa-mir-10b-3p
;
hsa-mir-6501-3p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-7977
;
hsa-mir-7154-5p
;
hsa-mir-6748-5p
;
hsa-mir-6769b-5p
;
hsa-mir-6769a-5p
;
hsa-mir-3165
;
hsa-mir-4483
;
hsa-mir-1293
;
hsa-mir-6766-5p
;
hsa-mir-6756-5p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-4680-5p
;
hsa-mir-8060
;
hsa-mir-383-3p
;
hsa-mir-4761-5p
;
hsa-mir-1273e
;
hsa-mir-1827
;
hsa-mir-3929
;
hsa-mir-4419b
;
hsa-mir-4478
;
hsa-mir-4649-3p
;
hsa-mir-4722-5p
;
hsa-mir-4768-3p
;
hsa-mir-485-5p
;
hsa-mir-658
;
hsa-mir-665
;
hsa-mir-6808-5p
;
hsa-mir-6840-3p
;
hsa-mir-6884-5p
;
hsa-mir-6893-5p
;
hsa-mir-7160-5p
;
hsa-mir-7846-3p
;
hsa-mir-940
Nearest miRNA
hsa-mir-107/Upstream/319737; hsa-mir-1307/Downstream/515278;
Nearest TSS
ENST00000439456/Upstream/31498;
ENST00000299238/Downstream/80830;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/77565
,
chr10-CpG: 72/Downstream/134511
Upstream sequence
ccacaatttaaaatcttaaaaacgttttttaaaaggattgaactactgatatataccacaaagtagatgaatctcaaaaacctgatattgagtgaaagaa
Downstream sequence
gtcagacacaaaagaaggcacactatatgactctgttcatatgtagttccagaacaggtacaactaatttgtggtgacagaaatcaggagagggcatagt
Target sequence
agactcaaagtagaatggtggttggcaggggctggggaaggggaaaatggggagttgtttaatcagtacaatttcagttttgcaagatgaaaaagttctagagatctgttgcacaacaatgtcaatatacttaatgctaccaaacttaacaaatcattaggatggcaaattttatatttcttaccacaatttaaaatcttaaaaacgttttttaaaaggattgaactactgatatataccacaaagtagatgaat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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