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TVIS30014712
Basic Information
VIS ID
TVIS30014712
Fusion event
HIV-SHOC2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
112731059/110971301 (Hg38)
End
112731450/110971301 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
;
FRA10A
;
FRA10B
Target gene
SHOC2
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-335-5p
;
hsa-mir-103a-3p
;
hsa-mir-26b-5p
;
hsa-mir-92a-3p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-299-3p
;
hsa-mir-20b-5p
;
hsa-mir-491-5p
;
hsa-mir-519c-3p
;
hsa-mir-526b-3p
;
hsa-mir-519b-3p
;
hsa-mir-519d-3p
;
hsa-mir-519a-3p
;
hsa-mir-575
;
hsa-mir-1825
;
hsa-mir-2110
;
hsa-mir-548t-5p
;
hsa-mir-3189-5p
;
hsa-mir-4668-5p
;
hsa-mir-4676-5p
;
hsa-mir-371b-3p
;
hsa-mir-4758-3p
;
hsa-mir-4786-3p
;
hsa-mir-5699-5p
;
hsa-mir-6124
;
hsa-mir-548az-5p
;
hsa-mir-6796-5p
;
hsa-let-7a-3p
;
hsa-let-7b-3p
;
hsa-let-7f-1-3p
;
hsa-mir-15a-5p
;
hsa-mir-98-3p
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-379-3p
;
hsa-mir-380-3p
;
hsa-mir-424-5p
;
hsa-mir-497-5p
;
hsa-mir-411-3p
;
hsa-mir-1245a
;
hsa-mir-3942-5p
;
hsa-mir-4495
;
hsa-mir-4703-5p
;
hsa-mir-6838-5p
;
hsa-mir-8062
;
hsa-mir-8079
;
hsa-mir-5000-5p
;
hsa-mir-216a-3p
;
hsa-mir-218-5p
;
hsa-mir-128-3p
;
hsa-mir-4302
;
hsa-mir-4291
;
hsa-mir-3611
;
hsa-mir-3681-3p
;
hsa-mir-7843-3p
;
hsa-mir-374a-5p
;
hsa-mir-374b-5p
;
hsa-mir-138-2-3p
;
hsa-mir-5197-5p
;
hsa-mir-219a-2-3p
;
hsa-mir-4539
;
hsa-mir-219b-3p
;
hsa-mir-4680-3p
;
hsa-mir-203b-3p
;
hsa-mir-200b-3p
;
hsa-mir-200c-3p
;
hsa-mir-429
;
hsa-mir-4639-5p
;
hsa-mir-488-5p
;
hsa-mir-1245b-3p
;
hsa-mir-5586-5p
;
hsa-mir-1264
;
hsa-mir-1185-2-3p
;
hsa-mir-1185-1-3p
;
hsa-let-7f-2-3p
;
hsa-mir-4789-5p
;
hsa-mir-4666a-3p
;
hsa-mir-381-3p
;
hsa-mir-300
;
hsa-mir-8485
;
hsa-mir-4731-3p
;
hsa-mir-4801
;
hsa-mir-944
;
hsa-mir-6742-5p
;
hsa-mir-4472
;
hsa-mir-4447
;
hsa-mir-3151-5p
;
hsa-mir-6780b-5p
;
hsa-mir-4725-3p
;
hsa-mir-4271
;
hsa-mir-3619-5p
;
hsa-mir-761
;
hsa-mir-214-3p
;
hsa-mir-922
;
hsa-mir-4657
;
hsa-mir-4491
;
hsa-mir-636
;
hsa-mir-4699-5p
;
hsa-mir-3120-3p
;
hsa-mir-127-5p
;
hsa-mir-548au-3p
;
hsa-mir-494-3p
;
hsa-mir-34a-5p
;
hsa-mir-34c-5p
;
hsa-mir-449b-5p
;
hsa-mir-449a
;
hsa-mir-4519
;
hsa-mir-548e-5p
;
hsa-mir-3942-3p
;
hsa-mir-7977
;
hsa-mir-24-3p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-342-3p
;
hsa-mir-383-3p
;
hsa-mir-4257
;
hsa-mir-6847-5p
;
hsa-mir-1228-3p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-4284
;
hsa-mir-665
;
hsa-mir-633
;
hsa-mir-7160-5p
;
hsa-mir-4722-5p
;
hsa-mir-1827
;
hsa-mir-4649-3p
;
hsa-mir-3664-3p
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4768-3p
;
hsa-mir-5690
;
hsa-mir-5692c
;
hsa-mir-5692b
;
hsa-mir-369-3p
;
hsa-mir-2114-5p
;
hsa-mir-5588-3p
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-4695-5p
;
hsa-mir-510-5p
;
hsa-mir-512-5p
;
hsa-mir-4803
;
hsa-mir-181d-5p
;
hsa-mir-181b-5p
;
hsa-mir-181c-5p
;
hsa-mir-181a-5p
;
hsa-mir-1262
;
hsa-mir-1273g-3p
;
hsa-mir-3160-3p
;
hsa-mir-3664-5p
;
hsa-mir-4252
;
hsa-mir-4487
;
hsa-mir-4522
;
hsa-mir-4701-3p
;
hsa-mir-4793-3p
;
hsa-mir-508-5p
;
hsa-mir-542-3p
;
hsa-mir-558
;
hsa-mir-6512-3p
;
hsa-mir-661
;
hsa-mir-6720-5p
;
hsa-mir-6736-5p
;
hsa-mir-6742-3p
;
hsa-mir-6776-5p
;
hsa-mir-6849-3p
;
hsa-mir-766-3p
;
hsa-mir-7703
Nearest miRNA
hsa-mir-107/Upstream/73146; hsa-mir-202/Downstream/17625;
Nearest TSS
ENST00000439456/Upstream/6269;
ENST00000280155/Downstream/105862;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/51165
,
chr10-CpG: 317/Downstream/104931
Upstream sequence
aattcattctgagttagttttttgtatatagtgagagataggggtctagtttcattcttctgcatatatatatatccagctttctcagtaccatttcttg
Downstream sequence
cattttttggtccctttgaatttctttcattgttttacagttttcatcatagagctttttcacctccttaaatttaCATTTAAGAATCAGCATTTTAAAA
Target sequence
aagggtctgtcctttcttcaatgtatattgttggctcctttatcaagtatcagttggctgtaaatatgtggatttatttctgggttctctactctattcaattgatctattgtcttgtttttatgccagtactgtgcattttggttactctaactttgtgtatactttgaggtcaggtagtgtgatgcctccaattttgtcctttttgcccagtattgctttggctatttagagtcttctatggttccacatgaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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