Basic Information
VIS ID
TVIS30014715
Fusion event
HIV-chr10 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q25.2
Reference genome
GRCh37/hg19
Start
112777978/111018220 (Hg38)
End
112778020/111018220 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/29207; hsa-mir-202/Downstream/1281392;
Nearest TSS
ENST00000439456/Upstream/53188; ENST00000280155/Downstream/58943;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/98084, chr10-CpG: 317/Downstream/58012
Nearby gene
SHOC2(No orient, 4553)
Upstream sequence
gtcttagcaatacatattagtaagaagtaatgattgagtgggtaaaatgactaaggatcaaagaatactcccagattagtggcttaagcatctgggtgta
Downstream sequence
ggtttgtttagaggtaggaagaaaatgtgttttagagcctgtggaacatcaagtggagataccaggtaagcaattggatacatacatgttaggaagttag
Target sequence
tttactaaactaaggaaacttggcagaggaccagattctttt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate