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TVIS30014717
Basic Information
VIS ID
TVIS30014717
Fusion event
HIV-ABLIM1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
116303540/114543781 (Hg38)
End
116303696/114543781 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
;
FRA10A
;
FRA10B
Target gene
ABLIM1
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-122-5p
;
hsa-mir-615-3p
;
hsa-mir-331-3p
;
hsa-mir-320a
;
hsa-mir-100-5p
;
hsa-mir-34a-5p
;
hsa-mir-5581-3p
;
hsa-mir-222-3p
;
hsa-mir-221-3p
;
hsa-mir-610
;
hsa-mir-556-5p
;
hsa-mir-499b-3p
;
hsa-mir-499a-3p
;
hsa-mir-4480
;
hsa-mir-6845-3p
;
hsa-mir-1226-3p
;
hsa-mir-512-3p
;
hsa-mir-216b-5p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-548c-3p
;
hsa-mir-8485
;
hsa-mir-4540
;
hsa-mir-6758-3p
;
hsa-mir-6891-3p
;
hsa-mir-6072
;
hsa-mir-6838-3p
;
hsa-mir-153-3p
;
hsa-mir-4276
;
hsa-mir-4766-3p
;
hsa-mir-152-3p
;
hsa-mir-148b-3p
;
hsa-mir-148a-3p
;
hsa-mir-3908
;
hsa-mir-4703-5p
;
hsa-mir-3942-5p
;
hsa-mir-6727-3p
;
hsa-mir-1281
;
hsa-mir-4763-3p
;
hsa-mir-6836-5p
;
hsa-mir-1207-5p
;
hsa-mir-6132
;
hsa-mir-660-3p
;
hsa-mir-5193
;
hsa-mir-3918
;
hsa-mir-1306-5p
;
hsa-mir-6895-5p
;
hsa-mir-603
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-411-5p
;
hsa-mir-3202
;
hsa-mir-4533
Nearest miRNA
hsa-mir-107/Upstream/369602; hsa-mir-202/Downstream/2283707;
Nearest TSS
ENST00000439456/Upstream/16850;
ENST00000436932/Downstream/31756;
Nearest CpG islands
None/Target,
chr10-CpG: 68/Upstream/138941
,
chr10-CpG: 46/Downstream/87926
Upstream sequence
atggcttcctaccgcttttagggtaacacccaaactccAGAATATGACTCTTGGGACCCTGCCCACTTCTCCAGCATCATCTGTCACATCGGTGCCCAAC
Downstream sequence
GCACACATCCAATGCTGGCCCCTCTGTGCTTCATGGAAAGGGTTTACAGTGGGATTTAGGGGGCTACACTGGGCCTTTGCTGTGAAACCCCACGGAAGAG
Target sequence
TGACGTTTCTTATGTATCCTGTGCTTTTCCTCACCTCTGAGCCTCTGCAGGTATTGCTCCCTCTTCCCAGAACCCTCTTCCTCGGGCTAAGAGGCAACTGCATTTGACCACAACCACACCCTTCTCTCCCAAATGCAATCAGCTGCCCACGTCCCA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT5
Sample type
PBMC
Age
44
Gender
Male
CpG Island Information
×
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