Basic Information
VIS ID
TVIS30014719
Fusion event
HIV-chr10 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.11
Reference genome
GRCh37/hg19
Start
120217011/118457499 (Hg38)
End
120217210/118457499 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Nearest miRNA
hsa-mir-107/Upstream/1289725; hsa-mir-202/Downstream/920473;
Nearest TSS
ENST00000439456/Upstream/99744; ENST00000340087/Downstream/137870;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/115074, chr10-CpG: 166/Downstream/136681
Nearby gene
FAM204A(No orient, 115172)
Upstream sequence
GGGTGGCCACACTATGATATATAGGTTGGATCTTCTAATTACTTAGCTGTAGCAATTAGGATTTTCTTTGTATTACACTTCTTCAGGCCAAAGATGCCTT
Downstream sequence
ATTTCAGGAGGCCTGTAGCCTTGGAGACGTGGAGTTCTGTTTTCATCGAATACAGTAGCTCCCAGACATTACTAGAGAAAGATCAGAAGGGGCAGGAGCT
Target sequence
CTATCGCTCGGGCCAGATTTAGGAGAGCAAATTCTGGCTTCCATCCCATTCCCCATTGCCATCCCCCAGCTGAAGCTGTTCTAAACTGGAGATCTTAAAGGCAAGTCCAATGCTGTGAGGAGGAGATGAGAGGAGAGTCACTGTGATGACCGCACTTGATGTCTCCTGGAAAGACCACTTTGCTTGGGGTCTCTTCTCC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate