Basic Information
VIS ID
TVIS30014723
Fusion event
HIV-PSMD13 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh37/hg19
Start
246110/246110 (Hg38)
End
246271/246110 (Hg38)
Orient
+
Location type
Intronic
Target gene
PSMD13
miRNAs that regulate target gene
hsa-mir-93-3p ; hsa-mir-615-3p ; hsa-mir-186-5p ; hsa-mir-183-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p
Nearest miRNA
hsa-mir-6743/Upstream/36704; hsa-let-7a-2/Downstream/321979;
Nearest TSS
ENST00000527297/Upstream/1681; ENST00000533717/Downstream/2497;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/8820, chr11-CpG: 268/Downstream/32962
Upstream sequence
TTCTCCCCCAGCCAGGCTCCCTCTCATGCCCATGCATTTCCTTGTCCTTCATTAAATAGGGGTGTGTAACTCAAGCGTTTTAACAttggctcaatactag
Downstream sequence
ggcaggtggatcacaaggtcaggagttcaagaccaacccagccaagatggtaaaaccccgtctctactaaaaccacaaaaattagccgggcatggtggcg
Target sequence
gtttcagagtcatgtgggtatgtgtaaccaatgtgctgttactcctatacggtatttcattgtataagtgtttcacaacatatgtatccagtctcctattgaagagatttagggccaggtgcgatggtcacacctgtaatcccagcactttgggaggctga
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate