Basic Information
VIS ID
TVIS30014725
Fusion event
HIV-TALDO1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.5
Reference genome
GRCh37/hg19
Start
757513/757513 (Hg38)
End
757373/757513 (Hg38)
Orient
-
Location type
Intronic
Target gene
TALDO1
miRNAs that regulate target gene
hsa-mir-935 ; hsa-mir-378a-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-210/Upstream/189315; hsa-let-7a-2/Downstream/499092;
Nearest TSS
ENST00000527297/Upstream/1769; ENST00000530666/Downstream/6469;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/9481, chr11-CpG: 20/Downstream/5679
Nearest cancer related gene
TALDO1(OG, No orient, 0)
Upstream sequence
tcccaagtagctgggactacaggtgcacgccaccacacctggctaatatttgtatttgtttttagaggcagggtttcaccatgttgccctagctggtttc
Downstream sequence
gaactcctgagcttgagcagtctgcccaccttggcctgccagggtgctgtgattacaggcgtgagccactgcacccagtcTGGCCCAAGAATTCTAACCT
Target sequence
cctctacatcctaggctcaagccagcctcccacctcagcctcccaagtagctgggactacaggtgcacgccaccacacctggctaatatttgtatttgtttttagaggcagggtttcaccatgttgccctagctggtttc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate