Basic Information
VIS ID
TVIS30014732
Fusion event
HIV-STIM1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
4082091/4060861 (Hg38)
End
4081982/4060861 (Hg38)
Orient
-
Location type
Intronic
Target gene
STIM1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-let-7b-5p ; hsa-mir-769-3p ; hsa-mir-17-3p ; hsa-mir-1231 ; hsa-mir-620 ; hsa-mir-1270 ; hsa-mir-3650 ; hsa-mir-4711-3p ; hsa-mir-4683 ; hsa-mir-1273f ; hsa-mir-6776-5p ; hsa-mir-6861-5p ; hsa-mir-4638-5p ; hsa-mir-6793-3p ; hsa-mir-185-5p ; hsa-mir-185-3p ; hsa-mir-1180-3p ; hsa-mir-1226-5p ; hsa-mir-1304-5p ; hsa-mir-1914-3p ; hsa-mir-3184-5p ; hsa-mir-423-5p ; hsa-mir-4778-3p ; hsa-mir-5194 ; hsa-mir-6734-5p ; hsa-mir-6738-5p ; hsa-mir-6783-5p ; hsa-mir-6834-5p ; hsa-mir-6850-3p ; hsa-mir-6875-3p ; hsa-mir-8055
Nearest miRNA
hsa-mir-210/Upstream/204720; hsa-let-7a-2/Downstream/3173905;
Nearest TSS
ENST00000527297/Upstream/2112; ENST00000533343/Downstream/13658;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/204660, chr11-CpG: 68/Downstream/33598
Upstream sequence
caacaaatatagtaaagtgtcaacaaatatagtaagtgttatagctattatgtaagtctttccagagttcaactgggggcacaaactagggaggagtttc
Downstream sequence
ctattggagtccagggaaactttatggagaaagtaattcttgagctgagtcttaaaagatgagaagTGGCCTTATTAAACTCTCCCTATGTTAACAGCTT
Target sequence
tagctatgtcaacaaatatagtaaagtgtcaacaaatatagtaagtgttatagctattatgtaagtctttccagagttcaactgggggcacaaactagggaggagtttc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate