Basic Information
VIS ID
TVIS30014733
Fusion event
HIV-chr11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
6745747/6724516 (Hg38)
End
6745920/6724516 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-210/Upstream/2868375; hsa-let-7a-2/Downstream/510250;
Nearest TSS
ENST00000527297/Upstream/41115; ENST00000307401/Downstream/44539;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/40804, chr11-CpG: 58/Downstream/201773
Nearby gene
GVINP1(No orient, 2637)
Upstream sequence
cgaggtgaacttaggcttaaggcaccacctagactgaaaaaggaggcagcaatctagtggtaaatattcactaaataaatatactaaataaaaaccagaa
Downstream sequence
gaaactcaattatctcaaaggtaaagcagttcagaagcatgtcagaaagtgtaacaaagagattgaaacaataattaaaaaaaattaaacaaaaatattg
Target sequence
caagccaaagaaagaaaactggaataaataacttctccttcaatgcaaaggcattggcacatgcccacaagaaacaacaacaatcagggagccattacctccacagaaagactaagcaaaaatccagtgactgactctaatgagatagtgatctgtgaattctctgcccaaga
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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