Basic Information
VIS ID
TVIS30014735
Fusion event
HIV-IPO7 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
9463849/9442302 (Hg38)
End
9463876/9442302 (Hg38)
Orient
+
Location type
Intronic
Target gene
IPO7
miRNAs that regulate target gene
hsa-mir-9-5p ; hsa-mir-16-5p ; hsa-mir-1226-3p ; hsa-mir-106b-5p ; hsa-mir-204-5p ; hsa-mir-92a-3p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-5696 ; hsa-mir-340-5p ; hsa-mir-513a-3p ; hsa-mir-582-5p ; hsa-mir-1229-3p ; hsa-mir-513c-3p ; hsa-mir-3606-3p ; hsa-mir-6511a-3p ; hsa-mir-6511b-3p ; hsa-mir-6784-3p ; hsa-mir-6862-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-579-3p ; hsa-mir-664b-3p ; hsa-mir-203a-3p ; hsa-mir-449c-3p ; hsa-mir-302f ; hsa-mir-5000-5p ; hsa-mir-6853-3p ; hsa-mir-8086 ; hsa-mir-205-5p ; hsa-mir-2681-5p ; hsa-mir-101-3p ; hsa-mir-195-3p ; hsa-mir-16-2-3p ; hsa-mir-455-5p ; hsa-mir-302b-5p ; hsa-mir-302d-5p ; hsa-mir-331-5p ; hsa-mir-33a-3p ; hsa-mir-411-5p ; hsa-mir-4278 ; hsa-mir-4450 ; hsa-mir-4678 ; hsa-mir-548ag ; hsa-mir-548ai ; hsa-mir-548ba ; hsa-mir-548m ; hsa-mir-570-5p ; hsa-mir-6783-5p ; hsa-mir-6789-5p ; hsa-mir-6824-5p ; hsa-mir-7-5p
Nearest miRNA
hsa-mir-210/Upstream/351923; hsa-let-7a-2/Downstream/1065968;
Nearest TSS
ENST00000527297/Upstream/8816; ENST00000527597/Downstream/18017;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/57147, chr11-CpG: 86/Downstream/18260
Upstream sequence
TTAATTAACTGTAACTCCTCTTTAATTAGTGACTTTTATAGGtttaaaattttatatcgtttaattttatatcattaaattttatCATTTAAGATGATAT
Downstream sequence
GAATTAACTCTAATCTGAGGGATTTAATTCAAGATAACTTAATTTTGGCTTTGGCTACAGTTGGCTTTTTTCGTTtttttttgtttgtttgtttgtttgt
Target sequence
AAAAGGTATAGTTGTTGCAGGTGATAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate