Basic Information
VIS ID
TVIS30014737
Fusion event
HIV-FAR1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
13703198/13681651 (Hg38)
End
13703238/13681651 (Hg38)
Orient
+
Location type
Intronic
Target gene
FAR1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-101-3p ; hsa-mir-93-3p ; hsa-mir-484 ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p
Nearest miRNA
hsa-mir-210/Upstream/1517884; hsa-let-7a-2/Downstream/2287882;
Nearest TSS
ENST00000527297/Upstream/12940; ENST00000532769/Downstream/13105;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/12474, chr11-CpG: 185/Downstream/280868
Upstream sequence
aaaggtgagagagcttttgcctagctcacaagaatactggtctttaagccattagcagctttgtaagtatctgactattctgaggtccccatgctataag
Downstream sequence
AGTCCGGAGCTAGAACTGCTCAGCCagaattgcttagctgagccctttacaaattcctaactcataaaaattgtggaagaaaataaaatggtggttgttt
Target sequence
gaagcccaaactatctcatggggaAAATCGAAGAGGCTAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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