Basic Information
VIS ID
TVIS30014742
Fusion event
HIV-IMMP1L integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
GRCh37/hg19
Start
31505013/31483466 (Hg38)
End
31505154/31483466 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11E
Target gene
IMMP1L
Nearest miRNA
hsa-mir-210/Upstream/3005918; hsa-let-7a-2/Downstream/3458371;
Nearest TSS
ENST00000527297/Upstream/27128; ENST00000638764/Downstream/26097;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/113515, chr11-CpG: 33/Downstream/26118
Upstream sequence
TAAATCCTTGTCATAAGAAATTTAGGAACTGACATGTATATAATCCAAGGGAGAAAACTGAGGGTTGTTACCGTATCTATTTGAATAACCAAATTTTCAA
Downstream sequence
CTTTTAAAATAGTCTCCGGACTGAAGATTTGCCTTTATATGTGGGAAACTAAAGTGGTACAGAATGCAGTATACAGAATATATGATTGCCGTTTTCACTC
Target sequence
CTACTTAGTTAACTTCCTGGATGCTTATAAATGGAAGACATTTATAACATTCACCCTATTATCTTCCCTTGATCCCAATCATGTATTCAGAGATATCCAGTCTTCGTGTTGGAAGTAACTGATACTGCTATTATAACACAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate