Basic Information
VIS ID
TVIS30014752
Fusion event
HIV-chr11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
47999905/47978353 (Hg38)
End
47999812/47978353 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/577311; hsa-let-7a-2/Downstream/118429;
Nearest TSS
ENST00000527297/Upstream/129798; ENST00000526550/Downstream/2205;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/129549, chr11-CpG: 177/Downstream/1699
Nearby gene
PTPRJ(No orient, 2204)
Nearest cancer related gene
PTPRJ(TSG, No orient, 2204)
Upstream sequence
ggcatgcgccactacacccagctcattttgtatttttagtagagacagggtttttccatgttggtcaggtggtcttgaactcccgacctcaggtgatccg
Downstream sequence
cccaccttagcctcccaaagtgctgggattataggcgtgagccactgtgcccagccCCCTGGTAGCATCTTAAATCAAGCTTTCCTTCCCTCTGGGTATC
Target sequence
gccactacacccagctcattttgtatttttagtagagacagggtttttccatgttggtcaggtggtcttgaactcccgacctcaggtgatccg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate