Basic Information
VIS ID
TVIS30014753
Fusion event
HIV-chr11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
59195260/59427787 (Hg38)
End
59195163/59427787 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/1786501; hsa-let-7a-2/Downstream/167290;
Nearest TSS
ENST00000527297/Upstream/1375; ENST00000302030/Downstream/8682;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/254208, chr11-CpG: 34/Downstream/132877
Nearby gene
OR5A2(No orient, 4834)
Upstream sequence
AAGGTAGATCTCACAGTTATGAAGGATACATTTTTCTAGGATTAGAAAAGGCTGATAAGggccgggcgcggtggctcatgcctgtaatcccagcactttg
Downstream sequence
ggaggccgaggcgggcagatcacgaggtcaggaaattgagactatcctagttaacacggtgaaaccccgtctctactaaaaatacaaacaaaaaaaaaat
Target sequence
GTAGATCTCACAGTTATGAAGGATACATTTTTCTAGGATTAGAAAAGGCTGATAAGggccgggcgcggtggctcatgcctgtaatcccagcactttg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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