Basic Information
VIS ID
TVIS30014754
Fusion event
HIV-chr11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
59327807/59560334 (Hg38)
End
59327827/59560334 (Hg38)
Orient
+
Location type
Intronic
Target gene
LINC02739 ; LOC102723575
Nearest miRNA
hsa-mir-129-2/Upstream/1919048; hsa-let-7a-2/Downstream/34743;
Nearest TSS
ENST00000527297/Upstream/45421; ENST00000531108/Downstream/5740;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/386755, chr11-CpG: 34/Downstream/330
Nearby gene
OSBP(No orient, 14063)
Upstream sequence
TTACACAATCCAGGACTTTATTCCCTTCTTTTGCAGTGTGTTAACAAACAAAAGATCCTAAAATTGGTTCTTACTCTTTTAATGAGGAAAAAAAAGATAC
Downstream sequence
ccctggaccctcagattaaaagtctgatgctctaccgactgagctatccgggcTCACGGTAGTAACGTTGCTTCCATTAATGAAGACTCTGTTACCATTA
Target sequence
cgcccgaacagggacttgaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate