Basic Information
VIS ID
TVIS30014755
Fusion event
HIV-LOC105369325 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
60797769/61030297 (Hg38)
End
60797583/61030297 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105369325
Nearest miRNA
hsa-mir-129-2/Upstream/821141; hsa-let-7a-2/Downstream/478299;
Nearest TSS
ENST00000527297/Upstream/13394; ENST00000536495/Downstream/25440;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/21462, chr11-CpG: 76/Downstream/130791
Nearby gene
CD6(No orient, 9921)
Upstream sequence
CAACATGCAGCCCTGGCTCTGAGAGAGAAAACATGGTCCCTGCCCTCAGAAGCTCAACAGCGTGGGCAGTCATGGGTCCTGGGATGGAAGAGCTCGCTTC
Downstream sequence
TCTGGATCCCAAAGTTCCTGGAGTCCCAGGAATCCAGAGGGGTGATTCAGGGCCAGCAGGTACCCCAGGAGCAGACACCCAGCAGTAGTGGCTCAGAACT
Target sequence
tgtgatcttcagagtcctgtccTATGGCTTCAAGTTCAGGAACATTTGTTTCGTGAAAGTTTAACTGACACTGTCAGGGCCAGTTCCAACATGCAGCCCTGGCTCTGAGAGAGAAAACATGGTCCCTGCCCTCAGAAGCTCAACAGCGTGGGCAGTCATGGGTCCTGGGATGGAAGAGCTCGCTTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate