Basic Information
VIS ID
TVIS30014757
Fusion event
HIV-LOC105369325 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
60813127/61045655 (Hg38)
End
60812904/61045655 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105369325
Nearest miRNA
hsa-mir-129-2/Upstream/836499; hsa-let-7a-2/Downstream/462941;
Nearest TSS
ENST00000527297/Upstream/28752; ENST00000536495/Downstream/10082;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/36820, chr11-CpG: 76/Downstream/115433
Nearby gene
CD6(No orient, 25279)
Upstream sequence
aatgtaaattgagagacagcttttaaaagcaactggaaaatgcgtaccgagggctttaacaatgcctgcgcttttgaccaggagacccacatttagaaac
Downstream sequence
tgccaagaaaacagtgtagacaaacatatacgcacaaagatgtccTCTACTATATAAGGAAAAACTAGAATGAGATGTCTAACATCTAGGAAACCCATCT
Target sequence
ACCAGCCTCCAGGTTGCCAGGCGTGCTCAAAGATGATTCATTAATTAGTAAGTATTTTTAAAAGACAGTCATCACGTCCATGAGATCGGggtcaaataggcactcccttgtgcttcaggttggaatgtaaattgagagacagcttttaaaagcaactggaaaatgcgtaccgagggctttaacaatgcctgcgcttttgaccaggagacccacatttagaaac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate