Basic Information
VIS ID
TVIS30014759
Fusion event
HIV-EEF1G integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
62333622/62566150 (Hg38)
End
62333263/62566150 (Hg38)
Orient
-
Location type
Intronic
Target gene
EEF1G
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-129-2/Upstream/687872; hsa-let-7a-2/Downstream/861;
Nearest TSS
ENST00000527297/Upstream/9915; ENST00000532626/Downstream/6593;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/18568, chr11-CpG: 39/Downstream/7606
Upstream sequence
ACAGAATATATATTTCTCAAACTGCTTGAACTCCCAATAAAATGACTTGGAGCAGTGATGGAAGAAAGACTCCATCCCAGAGAACTGGGCAAGCACTCAG
Downstream sequence
CGTCCTACATTTTTCATGCCAAAAATCTCGTTTTTACTATATTATTTCTTCCAAGAAGCCCTACCTTTAACTGAAAAAGGGATACAGAGGACACCTACTT
Target sequence
AACTTTCAGCTATACCCCAAGTTGCTCCCATCTATTAGTGCAATGCTTGTAATTCACAATTCTATGCACAGCTACTGTGTCCCTACCAGTGGGTGCTCCTTTAGGCTGGTTCACCCGGTATCCAAGCCATTACAAGATGGGAGAGGGTGAAATGTAAACCCTAGCAGACCAAGCAGTAAAAAGATGAACGGCTTTGGAAATGACAGGGTGAGTGGGAGGAAAAAGTACAGAGAAAGAGGAGTTCCAAAGCAAAGT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate