Basic Information
VIS ID
TVIS30014760
Fusion event
HIV-chr11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
62507520/62740048 (Hg38)
End
62507405/62740048 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-129-2/Upstream/172977; hsa-let-7a-2/Downstream/49767;
Nearest TSS
ENST00000527297/Upstream/100; ENST00000533442/Downstream/12051;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/12393, chr11-CpG: 39/Downstream/13850
Nearby gene
TTC9C(No orient, 1412)
Upstream sequence
ATTTtttctttttcttttaattttaagttccaggatccatgtgcaggatatgcaggtttgttacatagggaaacgtgtgcctcggtggtttgctgcacct
Downstream sequence
atcaacacatcacctcggtattaagtccagcatgtattagctatttttcctcatgttctcccaccccccgccacagccccTGTTAAATTAATTTCTTATT
Target sequence
TAACCATTTTGTTTAATTTtttctttttcttttaattttaagttccaggatccatgtgcaggatatgcaggtttgttacatagggaaacgtgtgcctcggtggtttgctgcacct
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate