Basic Information
VIS ID
TVIS30014766
Fusion event
HIV-chr11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
64493484/64726012 (Hg38)
End
64493415/64726012 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA11H
Nearest miRNA
hsa-mir-1237/Upstream/357309; hsa-let-7a-2/Downstream/152511;
Nearest TSS
ENST00000527297/Upstream/2824; ENST00000594089/Downstream/9254;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/2338, chr11-CpG: 320/Downstream/15949
Nearby gene
RASGRP2(No orient, 898)
Upstream sequence
AAGGGAGTGACCCAAAATAAAGAACAGGCCAGGGGGAGTGGGGTCTCAAAGCAGGGATGGATGTGATGTGGGGAAACCCTGGGGTGGGGGACCGGGGCAC
Downstream sequence
TCATGGGGGAACTGAGGCCACTGCCAGGCCCACAGATACTGTGCTTTGGAGTGGAAGGTGCTCAGGTCTCCACCCCTAGGACAATCCTACAGCTGCTGTG
Target sequence
GGGGGAGTGGGGTCTCAAAGCAGGGATGGATGTGATGTGGGGAAACCCTGGGGTGGGGGACCGGGGCAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate