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TVIS30014768
Basic Information
VIS ID
TVIS30014768
Fusion event
HIV-SF1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
64539318/64771846 (Hg38)
End
64539484/64771846 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
SF1
miRNAs that regulate target gene
hsa-mir-186-5p
;
hsa-mir-935
;
hsa-mir-320a
;
hsa-mir-221-3p
;
hsa-mir-544a
;
hsa-mir-6738-3p
;
hsa-mir-513a-3p
;
hsa-mir-513c-3p
;
hsa-mir-3606-3p
;
hsa-mir-3158-5p
;
hsa-mir-6859-3p
;
hsa-mir-4258
;
hsa-mir-489-3p
;
hsa-mir-548as-3p
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
;
hsa-mir-4294
;
hsa-mir-6124
;
hsa-mir-548ax
;
hsa-mir-548ao-5p
;
hsa-mir-3185
;
hsa-mir-802
;
hsa-mir-577
;
hsa-mir-651-3p
;
hsa-mir-7-2-3p
;
hsa-mir-7-1-3p
;
hsa-mir-5688
;
hsa-mir-495-3p
;
hsa-mir-3133
;
hsa-mir-539-5p
;
hsa-mir-17-3p
;
hsa-mir-1205
;
hsa-mir-1184
;
hsa-mir-3919
;
hsa-mir-3591-3p
;
hsa-mir-21-3p
;
hsa-mir-1262
;
hsa-mir-185-5p
;
hsa-mir-3150b-3p
;
hsa-mir-329-3p
;
hsa-mir-362-3p
;
hsa-mir-371a-5p
;
hsa-mir-3941
;
hsa-mir-4259
;
hsa-mir-4283
;
hsa-mir-4306
;
hsa-mir-4428
;
hsa-mir-4437
;
hsa-mir-4644
;
hsa-mir-4689
;
hsa-mir-4701-3p
;
hsa-mir-4710
;
hsa-mir-4784
;
hsa-mir-5195-5p
;
hsa-mir-571
;
hsa-mir-603
;
hsa-mir-6085
;
hsa-mir-6129
;
hsa-mir-6715a-3p
;
hsa-mir-6715b-3p
;
hsa-mir-6736-5p
;
hsa-mir-6741-5p
;
hsa-mir-6771-3p
;
hsa-mir-6813-5p
;
hsa-mir-6858-5p
;
hsa-mir-8485
Nearest miRNA
hsa-mir-1237/Upstream/403143; hsa-let-7a-2/Downstream/106677;
Nearest TSS
ENST00000527297/Upstream/239;
ENST00000594089/Downstream/5914;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/5555
,
chr11-CpG: 138/Downstream/5801
Upstream sequence
TGTTTTTACTGTGCAAGTTAAGCAGCATCAAAATAACAATAAAGTGGCTTAAGTGATATAACACCTTTTTAAGAAATTATCTTAATTAAGAAAACCCATG
Downstream sequence
TACAAAAACAAGTCTTACCAGCACCCAATTGGCCATGTGAAGGCCTCACAACAGTTTAACCTCCTCCCAAATTGCAGAAGTGAAAGGCAAAAGCTAGTAT
Target sequence
CATTTCCCTCCAACCTGGGCTCAAAAGCAAAACCAATCAGGCATTAGGGCCTCTTTCAAAACTGAATAGAAGGGAGGAAAAACCCTGCTCTGGTTTTATTTCTAACATGCTTGACATTTCTAATTCCCACCCCACAGCTGTCTAGAATTAAGCATTCTTAGCTAGT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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