VISDB Viral Integration Site DataBase

VIS ID

TVIS30014778

Fusion event

HIV-MALAT1 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr11

Cytoband

q13.1

Reference genome

Start

End

65267939/65500740 (Hg38)

Orient

-

Location type

Exonic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-9-5p ; hsa-mir-200c-3p ; hsa-mir-22-3p ; hsa-mir-23c ; hsa-mir-202-3p ; hsa-mir-1297 ; hsa-mir-204-5p ; hsa-mir-375 ; hsa-mir-146b-5p ; hsa-mir-200a-3p ; hsa-mir-200b-3p ; hsa-mir-141-3p ; hsa-mir-429

Nearest miRNA

hsa-mir-10392/Upstream/56183; hsa-let-7a-2/Downstream/135570;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/2813, chr11-CpG: 52/Downstream/24356

Nearest cancer related gene

MALAT1(OG, No orient, 0)

Upstream sequence

GGTGATGAAGGTAGCAGGCGGCTTGGCTTGGCAACCACACGGAGGAGGCGAGCAGGCGTTGTGCGTAGAGGATCCTAGACCAGCATGCCAGTGTGCCAAG

Downstream sequence

GCCACAGGGAAAGCGAGTGGTTGGTAAAAATCCGTGAGGTCGGCAATATGTTGTTTTTCTGGAACTTACTTATGGTAACCTTTTATTTATTTTCTAATAT

Target sequence

GATGAAGCTAGGACTGAGGAGCAAGCGAGCAAGCAGCAGTTCGTGGTGAAGATAGGAAAAGAGTCCAGGAGCCAGTGCGATTTGGTGAAGGAAGCTAGGAAGAAGGAAGGAGCGCTAACGATTTGGTGGTGAAGCTAGGAAAAAGGATTCCAGGAAGGAGCGAGTGCAATTTGGTGATGAAGGTAGCAGGCGGCTTGGCTTGGCAACCACACGGAGGAGGCGAGCAGGCGTTGTGCGTAGAGGATCCTAGACCAG