Basic Information
VIS ID
TVIS30014784
Fusion event
HIV-LOC105369350 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
65706151/65938680 (Hg38)
End
65705860/65938680 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
LOC105369350
Nearest miRNA
hsa-mir-10392/Upstream/289427; hsa-let-7a-2/Downstream/995754;
Nearest TSS
ENST00000527297/Upstream/17628; ENST00000531518/Downstream/6765;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/18597, chr11-CpG: 73/Downstream/22623
Nearby gene
TSGA10IP(No orient, 6963)
Upstream sequence
cacacacacacacacacacacacacGTCTATCTCTAAAATCACAAGATATTCAAATGGTACACTGGCTCAGGTCTTGGTTTTGCATCGGAGGCCAAGGAC
Downstream sequence
AAAGCAATAGCCCCAGGGCCCTGCATTGCTAATCAGGTGCCAGGCCCCCTTGCAGTGAGGACAGGACactcctgacctcaagtgatccacccacctcagc
Target sequence
gtgtttgacaaaaggacacaggtgatgtacattaggtgggtcagacagccaaacagtgatgatggtaaagactgggtggctctgtatgtcctgacatggaaagaATATAACATTCTAGTAGGCAAAACCAGGATGATCTCATTTTTGTTGAAAAATATGTATATGTAGGTTTGTATacacacacacacacacacacacacacacacacacacacacGTCTATCTCTAAAATCACAAGATATTCAAATGGTACACT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate