Basic Information
VIS ID
TVIS30014791
Fusion event
HIV-C11orf80 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
66559742/66792271 (Hg38)
End
66559565/66792271 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
C11orf80
miRNAs that regulate target gene
hsa-mir-6828-5p ; hsa-mir-7108-3p
Nearest miRNA
hsa-mir-10392/Upstream/1143018; hsa-let-7a-2/Downstream/142163;
Nearest TSS
ENST00000527297/Upstream/4111; ENST00000527352/Downstream/3626;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/29846, chr11-CpG: 91/Downstream/50624
Upstream sequence
TAGTTGTGTTGTATTAATTATCCTCTCTGACCTGACATTAGTCACTTTATCCTAACTCTGGGATAGGTGTCGGTCCTTCTGctgtattcctttagcacct
Downstream sequence
catttatctaaatttcacattgtcatataaattagtctgtctcatctactgaactgtgaactcttctaattctgagattgtcttatttatttttataagc
Target sequence
ccgccgcacccagcTTCCTCTCTCTAATAATTCTATGAGTAGATCTTAAAAGGGTCCTCTAACCCCTTTTAAGGGGTTAGTTGTGTTGTATTAATTATCCTCTCTGACCTGACATTAGTCACTTTATCCTAACTCTGGGATAGGTGTCGGTCCTTCTGctgtattcctttagcacct
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate