Basic Information
VIS ID
TVIS30014798
Fusion event
HIV-KDM2A integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.2
Reference genome
End
66987071/67219572 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-10392/Upstream/173864; hsa-let-7a-2/Downstream/270673;
Nearest cancer related gene
KDM2A(OG, No orient, 0)
Upstream sequence
TCACTGATGGTTTATCAAAACTTCCATTTTTCTTTCAGTTAAAATGCAGTGTTGACATTTTGGGAACACACaaaattttaaatttaattttttttttttt
Downstream sequence
ctagagtgcagtggcgtgatcatggatgattgcagcctcaacctcccaggctcaagcatcttcctgcctcagcctcccaagtagctgggaccgtgggtgc
Target sequence
aaggcagaatcttgttctgttttccagg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate