VISDB Viral Integration Site DataBase

VIS ID

TVIS30014799

Fusion event

HIV-KDM2A integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr11

Cytoband

q13.2

Reference genome

Start

End

66990442/67223245 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-16-5p ; hsa-mir-1226-3p ; hsa-mir-296-3p ; hsa-mir-769-5p ; hsa-mir-92b-3p ; hsa-mir-29b-3p ; hsa-mir-137 ; hsa-let-7i-3p ; hsa-mir-106b-3p ; hsa-mir-1273h-5p ; hsa-mir-1294 ; hsa-mir-1539 ; hsa-mir-185-5p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3122 ; hsa-mir-3134 ; hsa-mir-3150b-3p ; hsa-mir-3654 ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-377-5p ; hsa-mir-3913-5p ; hsa-mir-3939 ; hsa-mir-4306 ; hsa-mir-4464 ; hsa-mir-4477b ; hsa-mir-450a-1-3p ; hsa-mir-4534 ; hsa-mir-4644 ; hsa-mir-4683 ; hsa-mir-4693-3p ; hsa-mir-4695-3p ; hsa-mir-4748 ; hsa-mir-4784 ; hsa-mir-4802-5p ; hsa-mir-5192 ; hsa-mir-574-5p ; hsa-mir-6086 ; hsa-mir-6513-5p ; hsa-mir-655-5p ; hsa-mir-6731-5p ; hsa-mir-6740-5p ; hsa-mir-6746-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6788-5p ; hsa-mir-6878-5p ; hsa-mir-6894-5p ; hsa-mir-7154-3p ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-8082 ; hsa-mir-8085 ; hsa-mir-887-5p

Nearest miRNA

hsa-mir-10392/Upstream/177537; hsa-let-7a-2/Downstream/267000;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/103386, chr11-CpG: 17/Downstream/26891

Nearest cancer related gene

KDM2A(OG, No orient, 0)

Upstream sequence

cgtgccattgcactccagcctgggcgacaagaatgaaactccatctcaaaaaaaaaaaaaaaaaaTTATTTCCAAAAAATGCTAACCCAGTCTTAGAAAT

Downstream sequence

TGATATGCGGCATAAGTAAAAAGCAATGGGGTCAGGTTGGGTATGTGGTATCTCTTGGCTATAATTAATACAGTCTTATAAGTTACGAGTAAAAACTCAA

Target sequence

tacctgaggtcaggaagttgagaccagcgtgagcaacatgaagaaaccctgtctctactaaaaatacaaaattagccaggcgtggtggcacatgcctgtaatcccagctactcaggaggctgaggcaggaaaatcgcttgaacctgggaggcggaggttgcagtgagccaagatcgtgccattgcactccagcctgggcgacaagaatgaaactccatctcaaaaaaaaaaaaaaaaaaTTATTTCCAAAAAATG