VISDB Viral Integration Site DataBase

VIS ID

TVIS30014805

Fusion event

HIV-NUMA1 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr11

Cytoband

q13.4

Reference genome

Start

End

71744756/72033526 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-1208 ; hsa-mir-1252-5p ; hsa-mir-1911-3p ; hsa-mir-1972 ; hsa-mir-211-3p ; hsa-mir-4466 ; hsa-mir-4767 ; hsa-mir-6721-5p ; hsa-mir-6753-5p ; hsa-mir-675-5p ; hsa-mir-6760-3p ; hsa-mir-6816-3p ; hsa-mir-7112-3p ; hsa-mir-7112-5p ; hsa-mir-7113-5p

Nearest miRNA

hsa-mir-10392/Upstream/559958; hsa-let-7a-2/Downstream/38702;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/219719, chr11-CpG: 51/Downstream/46813

Upstream sequence

agtggcacgatcacagctcactgcagcttcaacctccacagcctcaggtgatcctcccacctcagcctcctaagtagctggaaccacaggagcacaccac

Downstream sequence

GTAGCTGCTATAAATAAAACTAGTCTTAggccaggcgcagtggctcatgcctacaatcctaacactttgggaggtcaaggcgggtggatcactggagctc

Target sequence

cacacccagctaatttttgtattttttgaagagacagggtctcaccacgttgcccagggtggttgcaaacttctgagctcaagtgatcctccacctcagcctcccaaagtgctggcattacaggtgtgagccactgcacctggccTCATGCATATTTATTGTGACTTTTCAGAAAAGGATGTAA