Basic Information
VIS ID
TVIS30014822
Fusion event
HIV-HIKESHI integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
86030829/86319787 (Hg38)
End
86030907/86319787 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11F
Target gene
HIKESHI
Nearest miRNA
hsa-mir-10392/Upstream/41389; hsa-let-7a-2/Downstream/1856715;
Nearest TSS
ENST00000527297/Upstream/13454; ENST00000529405/Downstream/23721;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/74312, chr11-CpG: 23/Downstream/54864
Upstream sequence
caattggttgatctctcaagtgtcttttaTACAAAGATAATGTATtctctcttctccatttccaagaaactacttggacttagaggtttaatcagatttt
Downstream sequence
tgtgtgaaacttagcagccatttgtttgtaatttattaattgagtaggggttcaaagtgataatattctaattttgtcattttttttaatatctgtaaag
Target sequence
agttttttaagttttggcaggattcttataggtggtggtgtgtttttccaccaggaagtacatatatggatatgtttt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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