Basic Information
VIS ID
TVIS30014827
Fusion event
HIV-chr11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q21
Reference genome
GRCh37/hg19
Start
95460944/95727780 (Hg38)
End
95461209/95727780 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-10392/Upstream/1261200; hsa-let-7a-2/Downstream/613658;
Nearest TSS
ENST00000527297/Upstream/29694; ENST00000538095/Downstream/51424;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/495356, chr11-CpG: 130/Downstream/61516
Nearby gene
FAM76B(No orient, 41161)
Upstream sequence
ACGATGAGATTGCTTCAATCCTGGGGAAAGCAGGGGGCAGGAGGCAGGAGGGAGCAAAGGCAAGAGCCCTGGGCAGCAGCATCTGCTTCTTTGGCACTGG
Downstream sequence
TGGAGTTCTCTGAGTATTGCCTCTTTACCATACTGTGTCATGGTACTTAATGGTAGGGAAGTTATTTTATGCATTTGTCTGCCCTTTCCTGAACACCTTC
Target sequence
GATATTTGGCAGTAGACCCTACCCTAGGCAGAAAAGCTGGGGCTGGAAAGAAGTAAAATGATAGTGTCTGGGGGCGGGGATGTTCTGGTGAAATACGCTGAGAATAACTCAGAAGTAATCCGTAAAGATTTTAAAGGAGTCTGGTGTGAACGAGGCAAAGCCAAAGGAATACCATATTTGGACTGCCATTCTGATGCTGTTGGCTTGGGAGACATGCTGTATATATCACTAGATATATGTGAATATCTTTCTATC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate