Basic Information
VIS ID
TVIS30014835
Fusion event
HIV-chr11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
104784287/104913560 (Hg38)
End
104784382/104913560 (Hg38)
Orient
+
Location type
Intronic
Nearest miRNA
hsa-mir-10392/Upstream/1063580; hsa-let-7a-2/Downstream/6434197;
Nearest TSS
ENST00000527297/Upstream/304239; ENST00000527177/Downstream/33632;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/749230, chr11-CpG: 31/Downstream/696839
Upstream sequence
aaaagcttttacgcagccaaagaaacatcaaaagattaaagagatatcaacagaattgggaaattatttgcaaaccatgcatctgataaggagttaatat
Downstream sequence
atatgtatatgaaaaatgatcagcctctgtaatcaccaggaaaattgaaaccacaatgtgatatcacttcacaccttttagaatggctactatcaaaaag
Target sequence
ggaaaatataaggaacacaaacaattaatagaaaacaaactgatttaaaaataaaggaccagaagagccatttttcagaagaagatatagaaaca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate