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TVIS30014838
Basic Information
VIS ID
TVIS30014838
Fusion event
HIV-ATM integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
108159694/108288967 (Hg38)
End
108159775/108288967 (Hg38)
Orient
+
Location type
Intronic
Target gene
ATM
miRNAs that regulate target gene
hsa-mir-421
;
hsa-mir-101-5p
;
hsa-mir-101-3p
;
hsa-mir-374a-5p
;
hsa-mir-181a-5p
;
hsa-mir-100-5p
;
hsa-mir-18a-5p
;
hsa-mir-19b-3p
;
hsa-mir-92a-3p
;
hsa-mir-3144-3p
;
hsa-mir-181b-5p
;
hsa-mir-106a-5p
;
hsa-mir-26a-5p
;
hsa-mir-223-3p
;
hsa-mir-181c-5p
;
hsa-mir-203a-3p
;
hsa-mir-18b-5p
;
hsa-mir-181d-5p
;
hsa-mir-4262
;
hsa-mir-4735-3p
;
hsa-mir-376c-3p
;
hsa-mir-377-3p
;
hsa-mir-432-5p
;
hsa-mir-218-5p
;
hsa-mir-7151-3p
;
hsa-mir-5095
;
hsa-mir-4537
;
hsa-mir-6504-3p
;
hsa-mir-4438
;
hsa-mir-7155-3p
;
hsa-mir-5007-3p
;
hsa-mir-3136-3p
;
hsa-mir-186-3p
;
hsa-mir-1279
;
hsa-mir-4747-3p
;
hsa-mir-543
;
hsa-mir-3133
;
hsa-mir-8070
;
hsa-mir-378a-5p
;
hsa-mir-572
;
hsa-mir-4454
;
hsa-mir-6759-3p
;
hsa-mir-3653-5p
;
hsa-mir-1306-5p
;
hsa-mir-30e-5p
;
hsa-mir-30d-5p
;
hsa-mir-30b-5p
;
hsa-mir-30c-5p
;
hsa-mir-30a-5p
;
hsa-mir-18a-3p
;
hsa-mir-1273e
;
hsa-mir-1827
;
hsa-mir-1910-3p
;
hsa-mir-219b-3p
;
hsa-mir-2467-3p
;
hsa-mir-302f
;
hsa-mir-3612
;
hsa-mir-3929
;
hsa-mir-4419b
;
hsa-mir-4459
;
hsa-mir-4478
;
hsa-mir-4649-3p
;
hsa-mir-4695-5p
;
hsa-mir-4722-5p
;
hsa-mir-4768-3p
;
hsa-mir-485-5p
;
hsa-mir-650
;
hsa-mir-6511a-5p
;
hsa-mir-665
;
hsa-mir-6746-5p
;
hsa-mir-6771-5p
;
hsa-mir-6808-5p
;
hsa-mir-6840-3p
;
hsa-mir-6884-5p
;
hsa-mir-6893-5p
;
hsa-mir-7160-5p
;
hsa-mir-940
Nearest miRNA
hsa-mir-10392/Upstream/4438987; hsa-let-7a-2/Downstream/3058790;
Nearest TSS
ENST00000527297/Upstream/1367;
ENST00000531957/Downstream/4418;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/65725
,
chr11-CpG: 101/Downstream/208804
Nearest cancer related gene
ATM
(TSG, No orient, 0)
Upstream sequence
TTTTGAATTTGGGGGTTATTAAAATCTAAATTTTCATTTTGGAAGTTCACTGGTCTATGAACAAAACTTTTTAAAACGATGACTGTATTTTTTCCCTTAA
Downstream sequence
CAATTGTCATAAAACCAAGTTAAAAAGCATTTTAGAAATTCTTTCCAAAAGCCCTGTAAGTATACATGATGAGTTTAATAATAGAACATTCCTTCTTTTT
Target sequence
CTCTGTTAGGGATTTGGATCCTGCTCCTAATCCACCTCATTTTCCATCGCATGTGATTAAAGCAACATTTGCCTATATCAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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