Basic Information
VIS ID
TVIS30014838
Fusion event
HIV-ATM integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
End
108159775/108288967 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-10392/Upstream/4438987; hsa-let-7a-2/Downstream/3058790;
Nearest cancer related gene
ATM(TSG, No orient, 0)
Upstream sequence
TTTTGAATTTGGGGGTTATTAAAATCTAAATTTTCATTTTGGAAGTTCACTGGTCTATGAACAAAACTTTTTAAAACGATGACTGTATTTTTTCCCTTAA
Downstream sequence
CAATTGTCATAAAACCAAGTTAAAAAGCATTTTAGAAATTCTTTCCAAAAGCCCTGTAAGTATACATGATGAGTTTAATAATAGAACATTCCTTCTTTTT
Target sequence
CTCTGTTAGGGATTTGGATCCTGCTCCTAATCCACCTCATTTTCCATCGCATGTGATTAAAGCAACATTTGCCTATATCAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate