Basic Information
VIS ID
TVIS30014842
Fusion event
HIV-chr11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
117005963/117135247 (Hg38)
End
117005934/117135247 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA11G ; FRA11B
Nearest miRNA
hsa-mir-10392/Upstream/3685159; hsa-let-7a-2/Downstream/1508753;
Nearest TSS
ENST00000527297/Upstream/36260; ENST00000533677/Downstream/9020;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/36451, chr11-CpG: 83/Downstream/8736
Nearby gene
PAFAH1B2(No orient, 9036)
Upstream sequence
taccatatcattttccacttgcaggtaggagacagggaccacgcccatcttatctttatattcccagcatctagtacagtgcctgaaatggaggaggtac
Downstream sequence
ccagtaaataatgttttggatgaatgaatGATTGAAGTTGCTCTGCTGGATTCTTATATTGTGTCTTGGGTATGTGTCGTCTTCCCAACTGCACTCGAAG
Target sequence
tagtacagtgcctgaaatggaggaggtac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate