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TVIS30014843
Basic Information
VIS ID
TVIS30014843
Fusion event
HIV-PAFAH1B2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
117041597/117170881 (Hg38)
End
117041843/117170881 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11G
;
FRA11B
Target gene
PAFAH1B2
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-30a-5p
;
hsa-mir-615-3p
;
hsa-mir-15a-5p
;
hsa-mir-103a-3p
;
hsa-mir-107
;
hsa-mir-15b-5p
;
hsa-mir-195-5p
;
hsa-mir-369-3p
;
hsa-mir-424-5p
;
hsa-mir-497-5p
;
hsa-mir-519d-5p
;
hsa-mir-4291
;
hsa-mir-5692a
;
hsa-mir-6074
;
hsa-mir-6838-5p
;
hsa-mir-7848-3p
;
hsa-mir-3613-3p
;
hsa-mir-3662
;
hsa-mir-2681-5p
;
hsa-mir-3646
;
hsa-mir-379-5p
;
hsa-mir-3163
;
hsa-mir-3935
;
hsa-mir-4451
;
hsa-mir-4650-3p
;
hsa-mir-3529-5p
;
hsa-mir-6764-3p
;
hsa-mir-6824-3p
;
hsa-mir-7705
;
hsa-mir-7852-3p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-130a-3p
;
hsa-mir-301a-3p
;
hsa-mir-130b-3p
;
hsa-mir-518a-5p
;
hsa-mir-527
;
hsa-mir-454-3p
;
hsa-mir-301b-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-4671-3p
;
hsa-mir-4477b
;
hsa-mir-559
;
hsa-mir-548b-5p
;
hsa-mir-548a-5p
;
hsa-mir-548c-5p
;
hsa-mir-548d-5p
;
hsa-mir-548j-5p
;
hsa-mir-548h-5p
;
hsa-mir-548i
;
hsa-mir-548w
;
hsa-mir-548y
;
hsa-mir-548o-5p
;
hsa-mir-548ab
;
hsa-mir-548ad-5p
;
hsa-mir-548ae-5p
;
hsa-mir-548ak
;
hsa-mir-548am-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548as-5p
;
hsa-mir-548au-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548bb-5p
;
hsa-mir-802
;
hsa-mir-3126-3p
;
hsa-mir-3128
;
hsa-mir-214-3p
;
hsa-mir-761
;
hsa-mir-922
;
hsa-mir-3619-5p
;
hsa-mir-187-5p
;
hsa-mir-221-3p
;
hsa-mir-222-3p
;
hsa-mir-506-5p
;
hsa-mir-2053
;
hsa-mir-548v
;
hsa-mir-4666a-5p
;
hsa-mir-892c-5p
;
hsa-mir-186-5p
;
hsa-mir-548k
;
hsa-mir-548l
;
hsa-mir-548av-5p
;
hsa-mir-8054
;
hsa-mir-5585-3p
;
hsa-mir-222-5p
;
hsa-mir-3609
;
hsa-mir-548ah-5p
;
hsa-mir-369-5p
;
hsa-mir-7856-5p
;
hsa-mir-6892-5p
;
hsa-mir-4668-5p
;
hsa-mir-3148
;
hsa-mir-329-5p
;
hsa-mir-5584-5p
;
hsa-mir-4475
;
hsa-mir-642a-5p
;
hsa-mir-2276-5p
;
hsa-mir-6892-3p
;
hsa-mir-4774-5p
;
hsa-mir-4490
;
hsa-mir-1273e
;
hsa-mir-137
;
hsa-mir-5588-5p
;
hsa-mir-4799-3p
;
hsa-mir-4720-5p
;
hsa-mir-6868-5p
;
hsa-mir-4470
;
hsa-mir-4680-5p
;
hsa-mir-569
;
hsa-mir-16-1-3p
;
hsa-mir-4714-3p
;
hsa-mir-1468-3p
;
hsa-mir-4719
;
hsa-mir-8063
;
hsa-mir-548p
;
hsa-mir-330-3p
;
hsa-mir-3145-3p
;
hsa-mir-6514-3p
;
hsa-mir-7977
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-564
;
hsa-mir-6847-3p
;
hsa-mir-6811-3p
;
hsa-mir-214-5p
;
hsa-mir-4755-3p
;
hsa-mir-4673
;
hsa-mir-4645-5p
;
hsa-mir-6715b-5p
;
hsa-mir-4269
;
hsa-mir-3622a-5p
;
hsa-mir-4753-5p
;
hsa-mir-8058
;
hsa-mir-5009-5p
Nearest miRNA
hsa-mir-10392/Upstream/3720793; hsa-let-7a-2/Downstream/1473119;
Nearest TSS
ENST00000527297/Upstream/11494;
ENST00000532960/Downstream/7852;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/26037
,
chr11-CpG: 37/Downstream/7802
Upstream sequence
AATATATGGAAATGAGGAGCATGTCCAAGCTCCTAAATCCGTGTGGGTGCATGTGGGAGAAGTGAGTTAGGGCCTCTTGAAAGGAGGCTTTTTGGAGAGG
Downstream sequence
GGAAATTGGATACTTAGATGATCCTGCTTCTTTACTGTGGAACTGAATGCACCAGGCTGACTCATCACTTACCTTCTCGGGCATGTAGATTGGTAGGGTG
Target sequence
GGTCCCCCAGGTTTCTTGGTGTTCCTGCTTGGGGATCACTGCTGCTAGCTGACTGGACCTCCCCATTGGAAGTTTGTGATTTTGCTTTGGCAAAGTTTCATTGACTAGTAGAACTCATTCTGTTTTAGTGTATATTTCAATATAAATGTAAACATTTTGCTCAATTTGCTGGTGTCTTTCTGTCTCCTTTATCATAGTTTGGATTCTAATGAAAAAAAGGGATGGTTTTTCCCTGCCTTATCATAA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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