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TVIS30014861
Basic Information
VIS ID
TVIS30014861
Fusion event
HIV-DDX6 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
118636882/118766174 (Hg38)
End
118636852/118766174 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11B
Target gene
DDX6
miRNAs that regulate target gene
hsa-mir-425-5p
;
hsa-mir-130b-3p
;
hsa-mir-124-3p
;
hsa-mir-1-3p
;
hsa-mir-26b-5p
;
hsa-mir-19b-3p
;
hsa-mir-877-3p
;
hsa-mir-505-3p
;
hsa-mir-484
;
hsa-mir-331-3p
;
hsa-mir-92a-3p
;
hsa-mir-16-5p
;
hsa-mir-145-5p
;
hsa-mir-143-3p
;
hsa-mir-218-5p
;
hsa-mir-2909
;
hsa-mir-4477b
;
hsa-mir-2053
;
hsa-mir-5089-3p
;
hsa-mir-1296-5p
;
hsa-mir-582-5p
;
hsa-mir-222-3p
;
hsa-mir-221-3p
;
hsa-mir-548v
;
hsa-mir-187-5p
;
hsa-mir-139-5p
;
hsa-mir-4277
;
hsa-mir-6834-3p
;
hsa-mir-5584-3p
;
hsa-mir-3158-3p
;
hsa-mir-4446-3p
;
hsa-mir-5088-5p
;
hsa-mir-6891-5p
;
hsa-mir-3173-3p
;
hsa-mir-4428
;
hsa-mir-759
;
hsa-mir-6868-3p
;
hsa-mir-1248
;
hsa-mir-1237-3p
;
hsa-mir-3613-3p
;
hsa-mir-6074
;
hsa-mir-548m
;
hsa-mir-216a-3p
;
hsa-mir-128-3p
;
hsa-mir-3681-3p
;
hsa-mir-148a-3p
;
hsa-mir-152-3p
;
hsa-mir-148b-3p
;
hsa-mir-19a-3p
;
hsa-mir-4665-5p
;
hsa-mir-1275
;
hsa-mir-4472
;
hsa-mir-4447
;
hsa-mir-92a-2-5p
;
hsa-mir-4525
;
hsa-mir-5010-5p
;
hsa-mir-7111-5p
;
hsa-mir-6870-5p
;
hsa-mir-5698
;
hsa-mir-4723-5p
;
hsa-mir-625-5p
;
hsa-mir-3175
;
hsa-mir-6134
;
hsa-mir-6878-5p
;
hsa-mir-558
;
hsa-mir-4311
;
hsa-mir-5011-5p
;
hsa-mir-190a-3p
;
hsa-mir-1277-5p
;
hsa-mir-1912
;
hsa-mir-1295b-5p
;
hsa-mir-587
;
hsa-mir-302c-5p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-202-5p
;
hsa-mir-337-3p
;
hsa-mir-4540
;
hsa-mir-3124-3p
;
hsa-mir-554
;
hsa-mir-6501-3p
;
hsa-mir-6838-3p
;
hsa-mir-646
;
hsa-mir-4520-3p
;
hsa-mir-6882-3p
;
hsa-mir-4638-3p
;
hsa-mir-335-5p
;
hsa-mir-548o-3p
;
hsa-mir-1323
;
hsa-mir-4272
;
hsa-mir-22-3p
;
hsa-mir-3654
;
hsa-mir-548f-3p
;
hsa-mir-548e-3p
;
hsa-mir-548az-3p
;
hsa-mir-548ar-3p
;
hsa-mir-548a-3p
;
hsa-mir-29a-3p
;
hsa-mir-29b-3p
;
hsa-mir-29c-3p
;
hsa-mir-4653-3p
;
hsa-mir-3924
;
hsa-mir-130a-3p
;
hsa-mir-28-3p
;
hsa-mir-301a-3p
;
hsa-mir-301b-3p
;
hsa-mir-3666
;
hsa-mir-3688-5p
;
hsa-mir-4295
;
hsa-mir-4302
;
hsa-mir-4524a-3p
;
hsa-mir-454-3p
;
hsa-mir-545-3p
;
hsa-mir-644a
;
hsa-mir-885-3p
;
hsa-mir-891a-3p
Nearest miRNA
hsa-mir-10392/Upstream/122095; hsa-let-7a-2/Downstream/144534;
Nearest TSS
ENST00000527297/Upstream/6805;
ENST00000610705/Downstream/24185;
Nearest CpG islands
None/Target,
chr11-CpG: 30/Upstream/131151
,
chr11-CpG: 140/Downstream/24422
Nearest cancer related gene
DDX6
(OG, No orient, 0)
Upstream sequence
taaaaaaaaagaaaagaaaCACTGCCCCTTATAATCTAGATACCGAGATGTATTAAAAAATTGGGCTGGGCAGCACAGTGAgtaactcatgcctagaatc
Downstream sequence
ccagcacttttggaggctgaggcaggaggatcgtttgagctcaggagtttaagaccagcctgggcaacatagcaagaccccatctctactaaaaaaaaaa
Target sequence
CAGCACAGTGAgtaactcatgcctagaatc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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