VISDB Viral Integration Site DataBase

VIS ID

TVIS30014863

Fusion event

HIV-DDX6 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr11

Cytoband

q23.3

Reference genome

Start

End

118636592/118766174 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-425-5p ; hsa-mir-130b-3p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-19b-3p ; hsa-mir-877-3p ; hsa-mir-505-3p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-mir-92a-3p ; hsa-mir-16-5p ; hsa-mir-145-5p ; hsa-mir-143-3p ; hsa-mir-218-5p ; hsa-mir-2909 ; hsa-mir-4477b ; hsa-mir-2053 ; hsa-mir-5089-3p ; hsa-mir-1296-5p ; hsa-mir-582-5p ; hsa-mir-222-3p ; hsa-mir-221-3p ; hsa-mir-548v ; hsa-mir-187-5p ; hsa-mir-139-5p ; hsa-mir-4277 ; hsa-mir-6834-3p ; hsa-mir-5584-3p ; hsa-mir-3158-3p ; hsa-mir-4446-3p ; hsa-mir-5088-5p ; hsa-mir-6891-5p ; hsa-mir-3173-3p ; hsa-mir-4428 ; hsa-mir-759 ; hsa-mir-6868-3p ; hsa-mir-1248 ; hsa-mir-1237-3p ; hsa-mir-3613-3p ; hsa-mir-6074 ; hsa-mir-548m ; hsa-mir-216a-3p ; hsa-mir-128-3p ; hsa-mir-3681-3p ; hsa-mir-148a-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-19a-3p ; hsa-mir-4665-5p ; hsa-mir-1275 ; hsa-mir-4472 ; hsa-mir-4447 ; hsa-mir-92a-2-5p ; hsa-mir-4525 ; hsa-mir-5010-5p ; hsa-mir-7111-5p ; hsa-mir-6870-5p ; hsa-mir-5698 ; hsa-mir-4723-5p ; hsa-mir-625-5p ; hsa-mir-3175 ; hsa-mir-6134 ; hsa-mir-6878-5p ; hsa-mir-558 ; hsa-mir-4311 ; hsa-mir-5011-5p ; hsa-mir-190a-3p ; hsa-mir-1277-5p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-587 ; hsa-mir-302c-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-202-5p ; hsa-mir-337-3p ; hsa-mir-4540 ; hsa-mir-3124-3p ; hsa-mir-554 ; hsa-mir-6501-3p ; hsa-mir-6838-3p ; hsa-mir-646 ; hsa-mir-4520-3p ; hsa-mir-6882-3p ; hsa-mir-4638-3p ; hsa-mir-335-5p ; hsa-mir-548o-3p ; hsa-mir-1323 ; hsa-mir-4272 ; hsa-mir-22-3p ; hsa-mir-3654 ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-4653-3p ; hsa-mir-3924 ; hsa-mir-130a-3p ; hsa-mir-28-3p ; hsa-mir-301a-3p ; hsa-mir-301b-3p ; hsa-mir-3666 ; hsa-mir-3688-5p ; hsa-mir-4295 ; hsa-mir-4302 ; hsa-mir-4524a-3p ; hsa-mir-454-3p ; hsa-mir-545-3p ; hsa-mir-644a ; hsa-mir-885-3p ; hsa-mir-891a-3p

Nearest miRNA

hsa-mir-10392/Upstream/122095; hsa-let-7a-2/Downstream/144534;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/131151, chr11-CpG: 140/Downstream/24422

Nearest cancer related gene

DDX6(OG, No orient, 0)

Upstream sequence

taaaaaaaaagaaaagaaaCACTGCCCCTTATAATCTAGATACCGAGATGTATTAAAAAATTGGGCTGGGCAGCACAGTGAgtaactcatgcctagaatc

Downstream sequence

ccagcacttttggaggctgaggcaggaggatcgtttgagctcaggagtttaagaccagcctgggcaacatagcaagaccccatctctactaaaaaaaaaa

Target sequence

gaccagcctgaccctatctctactaaaaatacaaaattagctgggcgtgggtggcacatgcctgtaatcccagctacttgggaggctgaggcagaagaatcgcttgaacccgagaggcagagattgtggtgagccgagattgtgccactgcactccagtccaggcaacaagagcgaaactccgtctcaaataaaaaaaaagaaaagaaaCACTGCCCCTTATAATCTAGATACCGAGATGTATTAAAAAATTGGG