Basic Information
VIS ID
TVIS30014872
Fusion event
HIV-chr11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
128125228/128255333 (Hg38)
End
128125050/128255333 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-let-7a-2/Upstream/1266791; hsa-mir-4697/Downstream/267057;
Nearest TSS
ENST00000527297/Upstream/43896; ENST00000525706/Downstream/208617;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1251419, chr11-CpG: 20/Downstream/196433
Nearby gene
ETS1(No orient, 203427)
Nearest cancer related gene
ETS1(OG, No orient, 203427)
Upstream sequence
aaacaaaacaaaccatcaaaagcaacagaaaaaaattagtaggaaaatgaaatacataaaatgttgacaggttggtcaatgcaaaatggaactttcaagt
Downstream sequence
aattaatctaagagtaaaaatttgatgtaattgcagatgacataggcttttaaaaattaaaagacaatataaggaacattggcgtgtaataaatttgaca
Target sequence
tttagaaaatctgagtaattccaagaaaaatagaaagaagaaaataataaacatgaaagaatacattaatgaaacattaaacaaaacaaaccatcaaaagcaacagaaaaaaattagtaggaaaatgaaatacataaaatgttgacaggttggtcaatgcaaaatggaactttcaagt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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