Basic Information
VIS ID
TVIS30014878
Fusion event
HIV-KDM5A integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
End
427948/318534 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-let-7i/Downstream/1341781;
Nearest cancer related gene
KDM5A(TSG, No orient, 0)
Upstream sequence
AAACTCTTCCACATCATCTAGCAGATTCTGAAAAGGTCAAAAGAAATAAAAATCAGAAAAACAAATTTAAAACATACAAAAGAGTATGAAATAGACATAG
Downstream sequence
atgcagatgaccagacagtgaacataggaataaaatgtttcagttagtgtcaagcgctctgaaaataaaatagggcagcacaacagagaatgaccagagt
Target sequence
TCAAGGCAAACTATCAATTCTAGACTCTTATAATCTCACCATCATAACACCAAATATTCAGATATGACAGTTAAATTAATAAATATGCTTTTGTGTAATTACTTCTAGCTATTCTCCTACTTTTAAAATATAGttgattcattcaataaatatttaatgactgctgacttagatgcaggcacttttctaggcacacagtattaaagaagacataaaatagtccttgtcttcagagaacatacattcta
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate