Basic Information
VIS ID
TVIS30014879
Fusion event
HIV-WNK1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.33
Reference genome
End
899928/790825 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-215-5p ; hsa-mir-21-5p ; hsa-mir-877-3p ; hsa-mir-550a-5p ; hsa-mir-106b-3p ; hsa-mir-93-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-193b-3p ; hsa-mir-423-3p ; hsa-mir-331-3p ; hsa-mir-378a-3p ; hsa-mir-320a ; hsa-mir-186-5p ; hsa-mir-149-5p ; hsa-mir-125b-5p ; hsa-mir-183-5p ; hsa-mir-197-3p ; hsa-let-7b-5p ; hsa-let-7a-3p ; hsa-let-7b-3p ; hsa-let-7f-1-3p ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-32-3p ; hsa-mir-98-3p ; hsa-mir-381-3p ; hsa-mir-590-3p ; hsa-mir-300 ; hsa-mir-1297 ; hsa-mir-4465 ; hsa-mir-4666a-3p ; hsa-mir-7849-3p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-155-5p ; hsa-mir-548a-3p ; hsa-mir-606 ; hsa-mir-548e-3p ; hsa-mir-548f-3p ; hsa-mir-302f ; hsa-mir-4639-5p ; hsa-mir-4775 ; hsa-mir-548ar-3p ; hsa-mir-548az-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-199a-5p ; hsa-mir-5007-3p ; hsa-mir-6755-3p ; hsa-mir-302a-5p ; hsa-mir-1279 ; hsa-mir-892c-3p ; hsa-mir-4676-3p ; hsa-mir-452-5p ; hsa-mir-5582-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-mir-4789-5p ; hsa-let-7f-2-3p ; hsa-mir-101-3p ; hsa-mir-4272 ; hsa-mir-5697 ; hsa-mir-144-3p ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-2682-3p ; hsa-mir-6781-3p ; hsa-mir-6823-3p ; hsa-mir-2114-3p ; hsa-mir-134-3p ; hsa-mir-7114-5p ; hsa-mir-130b-5p ; hsa-mir-6849-3p ; hsa-mir-6877-3p ; hsa-mir-6819-3p ; hsa-mir-4700-3p ; hsa-mir-6772-3p ; hsa-mir-6780a-3p ; hsa-mir-6509-3p ; hsa-mir-4795-3p ; hsa-mir-4477a ; hsa-mir-4448 ; hsa-mir-4268 ; hsa-mir-6797-3p ; hsa-mir-6076 ; hsa-mir-3188 ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-2467-5p ; hsa-mir-3975 ; hsa-mir-4774-5p ; hsa-mir-4490 ; hsa-mir-6824-3p ; hsa-mir-6764-3p ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-8063 ; hsa-mir-126-5p ; hsa-mir-944 ; hsa-mir-7-2-3p ; hsa-mir-7-1-3p ; hsa-mir-506-3p ; hsa-mir-141-5p ; hsa-mir-24-1-5p
Nearest miRNA
hsa-let-7i/Downstream/869490;
Upstream sequence
TTAGTGTTACTATGAGTTTATAGCCTGTTATTTTGTTTAGTGTTTACTCTGTcttgcctttcttttttccttccttcctttccttttctttcttttcttt
Downstream sequence
tGGAAGGGAACTTAAGTACATCTTCTGGTTCTTTCTGCCTGATCTCTTCCTCTTAATTTTAGAAATGAAGATGTAGAAGTCCAAAGAGGATTTACTTGAT
Target sequence
TAGTGTTTACTCTGTcttgcctttcttttttccttccttcctttccttttctttcttttcttt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate