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VISDB
Viral Integration Site DataBase
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TVIS30014887
Basic Information
VIS ID
TVIS30014887
Fusion event
HIV-CLEC2D integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
9845186/9692590 (Hg38)
End
9845378/9692590 (Hg38)
Orient
+
Location type
Intronic
Target gene
CLEC2D
miRNAs that regulate target gene
hsa-mir-2681-5p
;
hsa-mir-4477a
;
hsa-mir-4682
;
hsa-mir-6767-3p
;
hsa-mir-205-3p
;
hsa-mir-429
;
hsa-mir-200c-3p
;
hsa-mir-200b-3p
;
hsa-mir-4455
;
hsa-mir-6083
;
hsa-mir-1277-5p
;
hsa-mir-297
;
hsa-mir-3924
;
hsa-mir-567
;
hsa-mir-190a-3p
;
hsa-mir-5011-5p
;
hsa-mir-410-3p
;
hsa-mir-8066
;
hsa-mir-6867-5p
;
hsa-mir-3688-3p
;
hsa-mir-5680
;
hsa-mir-4662b
;
hsa-mir-4426
;
hsa-mir-4647
;
hsa-mir-3646
;
hsa-mir-6838-5p
;
hsa-mir-424-5p
;
hsa-mir-497-5p
;
hsa-mir-195-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-5003-3p
;
hsa-mir-587
;
hsa-mir-6818-3p
;
hsa-mir-5581-3p
;
hsa-mir-4286
;
hsa-mir-4716-5p
;
hsa-mir-1252-3p
;
hsa-mir-1910-3p
;
hsa-mir-214-3p
;
hsa-mir-3617-3p
;
hsa-mir-3619-5p
;
hsa-mir-3714
;
hsa-mir-4291
;
hsa-mir-577
;
hsa-mir-6511a-5p
;
hsa-mir-761
;
hsa-mir-922
Nearest miRNA
hsa-mir-1244-3/Upstream/453039; hsa-let-7i/Downstream/2419362;
Nearest TSS
ENST00000382841/Upstream/4689;
ENST00000541404/Downstream/11487;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/44334
,
chr12-CpG: 37/Downstream/418886
Upstream sequence
gacaggtgccaagaatgtcatagtagcatacattccaaacttgataaaaccctggtgtcaaccgatagtataatagataaattggagaagagtcatacaa
Downstream sequence
GGGTTATGTTAGATTAATGAATATCATCTCTGTGTTTTCTGAAAGAATTTCCTGTTGAGATATAAAGGCCCATCTGATCACTGGATTGGGCTGAGCAGAG
Target sequence
aggagtacaatacagaaacaaaagtaaccaaattaTCAACAATTTCTCTCAGTTTTAAATTATCTTCTTTTGATATGTATGATAATATAGCACACCTATTCTGTATGTATTACTAAACAATACAAAATCAAAAGGAAGAAAATTATGAGTAGTTAAGAATATAGCATAGCAGCAACATTTCTGGGAGAGGAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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