Basic Information
VIS ID
TVIS30014888
Fusion event
HIV-CD69 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
9905287/9752691 (Hg38)
End
9905254/9752691 (Hg38)
Orient
-
Location type
Exonic
Target gene
CD69
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p
Nearest miRNA
hsa-mir-1244-3/Upstream/513140; hsa-let-7i/Downstream/2359261;
Nearest TSS
ENST00000382841/Upstream/19392; ENST00000537723/Downstream/8210;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/104435, chr12-CpG: 37/Downstream/358785
Upstream sequence
GAAGTATTGAAGTATTGCACGTAATAGAATTGATTTAGGAAAGTCACAAACCTATTATAAGACTAGTATTATTCTAGGTCTGAAGATTACAGAATATTTC
Downstream sequence
CTAATAGAGATTTGCCACATCACATATTGCACATTTTCCAACACTATTCTATGTCTTGCAAATATTCCTCATAGTCTTTGCTTATGTCTTTTCTCTGTAA
Target sequence
ATTATTCTAGGTCTGAAGATTACAGAATATTTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate