Basic Information
VIS ID
TVIS30014889
Fusion event
HIV-chr12 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.31
Reference genome
GRCh37/hg19
Start
9924832/9772236 (Hg38)
End
9924791/9772236 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/532685; hsa-let-7i/Downstream/2339716;
Nearest TSS
ENST00000382841/Upstream/11335; ENST00000537723/Downstream/55245;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/123980, chr12-CpG: 37/Downstream/339240
Nearby gene
CD69(No orient, 11335)
Upstream sequence
ttgaagtctgcttctcaggggacccaaagtaacacaCTTTGTCTGGTACGTATAGTTAGAAAAATTGTAGAGTTTTTATCGGAAATTGATCACTCATAAC
Downstream sequence
CAAACATCTTGCAGTATGCCTGGAGGCAGAGCCGTAATATCactgggaaactcatcttcatgctgataatttctccaaggtgtgattattttccacatac
Target sequence
AAAAATTGTAGAGTTTTTATCGGAAATTGATCACTCATAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate