Basic Information
VIS ID
TVIS30014892
Fusion event
HIV-BORCS5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.2
Reference genome
End
12605617/12452983 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1244-3/Upstream/340947; hsa-let-7i/Downstream/311666;
Upstream sequence
TGTCTGAATCTCTACTGCAGGTCAAGTAGCCATGGTCTGGTGGGGATAGAGGTGGCAGGTGGGCTAGAACGTGCCATATCTTGATTTGTGGCAATGGGCC
Downstream sequence
TCCTACTCTTCGGAGTGGAGACAGCTAATACCATGAGTCAAAGACCAAATCGGGATAGCCGATGTATAAAAACACAAGCACCGGGTTTGCAaactggaag
Target sequence
GTGCCATTCAGCCTGTGGCGTAATTAAGGAAAACATTTGCCCATTGTTGTCCATTGTGCTAGAGAGAGGCGTCCAGGAAAGATTCATACTCCCAAACCCTCCATGGGAGTGGTGATCTGGAGAGGGTCGGACAGCCAGAAAGCACATAGTTGACCCTGAAAGGTTTTGTTGCAGCCTGTCATACCCTAACCTTTATAATCTGTCTGAATCTCTACTGCAGGTCAAGTAGCCATGGTCTGGTGGGGATAGAGGTGG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate