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TVIS30014894
Basic Information
VIS ID
TVIS30014894
Fusion event
HIV-BORCS5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
12612377/12459443 (Hg38)
End
12612662/12459443 (Hg38)
Orient
+
Location type
Intronic
Target gene
BORCS5
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-4474-3p
;
hsa-mir-7108-5p
;
hsa-mir-6870-3p
;
hsa-mir-205-5p
;
hsa-mir-6793-3p
;
hsa-mir-4793-5p
;
hsa-mir-5196-3p
;
hsa-mir-6729-3p
;
hsa-mir-500b-5p
;
hsa-mir-362-5p
;
hsa-mir-640
;
hsa-mir-1299
;
hsa-mir-378a-5p
;
hsa-mir-6821-3p
;
hsa-mir-6790-3p
;
hsa-mir-6128
;
hsa-mir-875-3p
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-3653-5p
;
hsa-mir-6777-3p
;
hsa-mir-3934-5p
;
hsa-mir-764
;
hsa-mir-125a-3p
;
hsa-mir-7107-5p
;
hsa-mir-1234-3p
;
hsa-mir-4725-5p
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-5699-3p
;
hsa-mir-4421
;
hsa-mir-339-5p
;
hsa-mir-10b-5p
;
hsa-mir-10a-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/347407; hsa-let-7i/Downstream/305206;
Nearest TSS
ENST00000382841/Upstream/102025;
ENST00000544086/Downstream/25910;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/101949
,
chr12-CpG: 111/Downstream/102256
Upstream sequence
cttgttgcccaggctggagtgcaatggcataatctcggctcactgcaacctctaccttccaggttcaagtgattctcctgcctcagcctcccaagtagct
Downstream sequence
gctccaggttcattctttctctttgtggatatctagatattctagcacaaattgttgaaaaacttttttcccccattaaattgccttgagatctttgtaa
Target sequence
gggactataggcatgcaccaccacctccagctaatgttttgtatttagtagagacgggatttcaccatgttggtcaggctcgtctcgaactgctgacctcagatgatccacccgtctcagcctcccaaagctctgggattacaggcgtgagccactgagtccagccaaggtagcaaagatttttctcctatattttcttctagaagttttatagttttagcttccatatttaggtctgtgatccattccatatta
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT4
Sample type
PBMC
Age
39
Gender
Male
CpG Island Information
×
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