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TVIS30014896
Basic Information
VIS ID
TVIS30014896
Fusion event
HIV-CDKN1B integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
12874085/12721151 (Hg38)
End
12874164/12721151 (Hg38)
Orient
+
Location type
Exonic
Target gene
CDKN1B
miRNAs that regulate target gene
hsa-mir-222-3p
;
hsa-mir-221-3p
;
hsa-mir-181a-5p
;
hsa-mir-24-3p
;
hsa-mir-192-5p
;
hsa-mir-196a-5p
;
hsa-mir-190a-5p
;
hsa-mir-218-5p
;
hsa-mir-128b
;
hsa-mir-98-5p
;
hsa-mir-1260b
;
hsa-mir-148a-3p
;
hsa-mir-194-5p
;
hsa-mir-182-5p
;
hsa-mir-200b-3p
;
hsa-mir-452-5p
;
hsa-mir-2355-5p
;
hsa-mir-548v
;
hsa-mir-187-5p
;
hsa-mir-6793-3p
;
hsa-mir-186-3p
;
hsa-mir-570-5p
;
hsa-mir-548ba
;
hsa-mir-548ai
;
hsa-mir-548ag
;
hsa-mir-561-3p
;
hsa-mir-548m
;
hsa-mir-548x-3p
;
hsa-mir-548j-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548ae-3p
;
hsa-mir-548z
;
hsa-mir-548h-3p
;
hsa-mir-548d-3p
;
hsa-mir-548bb-3p
;
hsa-mir-548ac
;
hsa-mir-455-5p
;
hsa-mir-4789-5p
;
hsa-mir-4672
;
hsa-mir-6768-5p
;
hsa-mir-3148
;
hsa-mir-651-3p
;
hsa-mir-196b-5p
;
hsa-mir-3658
;
hsa-mir-1303
;
hsa-mir-448
;
hsa-mir-5696
;
hsa-mir-153-3p
;
hsa-mir-6866-5p
;
hsa-mir-155-5p
;
hsa-mir-1909-5p
;
hsa-mir-1827
;
hsa-mir-4729
;
hsa-mir-1288-5p
;
hsa-mir-519e-3p
;
hsa-mir-515-3p
;
hsa-mir-33b-3p
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-5694
;
hsa-mir-302f
;
hsa-mir-877-5p
;
hsa-mir-335-3p
;
hsa-mir-30e-3p
;
hsa-mir-30d-3p
;
hsa-mir-30a-3p
;
hsa-mir-3591-5p
;
hsa-mir-4276
;
hsa-mir-5701
;
hsa-mir-4255
;
hsa-mir-590-3p
;
hsa-mir-4282
;
hsa-mir-142-3p
;
hsa-mir-152-3p
;
hsa-mir-148b-3p
;
hsa-mir-3147
;
hsa-mir-4652-3p
;
hsa-mir-4743-3p
;
hsa-mir-6763-5p
;
hsa-mir-3150a-3p
;
hsa-mir-6825-5p
;
hsa-mir-939-5p
;
hsa-mir-1343-5p
;
hsa-mir-3175
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-449b-5p
;
hsa-mir-449a
;
hsa-mir-34c-5p
;
hsa-mir-34a-5p
;
hsa-mir-5191
;
hsa-mir-3140-3p
;
hsa-mir-3616-3p
;
hsa-mir-3605-5p
;
hsa-mir-3679-5p
;
hsa-mir-1185-5p
;
hsa-mir-367-5p
;
hsa-mir-1267
;
hsa-mir-8089
;
hsa-mir-4700-5p
;
hsa-mir-4667-5p
;
hsa-mir-329-5p
;
hsa-mir-4464
;
hsa-mir-4748
;
hsa-mir-7843-5p
;
hsa-mir-6879-5p
;
hsa-mir-6735-5p
;
hsa-mir-4632-5p
;
hsa-mir-4436b-3p
;
hsa-mir-4463
;
hsa-mir-4685-3p
;
hsa-mir-4287
;
hsa-mir-6734-3p
;
hsa-mir-5088-3p
;
hsa-mir-3912-5p
;
hsa-mir-5581-3p
;
hsa-mir-1185-2-3p
;
hsa-mir-1185-1-3p
;
hsa-let-7f-2-3p
;
hsa-mir-98-3p
;
hsa-let-7f-1-3p
;
hsa-let-7b-3p
;
hsa-let-7a-3p
;
hsa-mir-219b-5p
;
hsa-mir-8060
;
hsa-mir-1265
;
hsa-mir-4700-3p
;
hsa-mir-520f-3p
;
hsa-mir-302c-3p
;
hsa-mir-4742-5p
;
hsa-mir-7852-3p
;
hsa-mir-7151-5p
;
hsa-mir-429
;
hsa-mir-200c-3p
;
hsa-mir-4676-3p
;
hsa-mir-892c-3p
;
hsa-mir-148a-5p
;
hsa-mir-221-5p
;
hsa-mir-323a-3p
;
hsa-mir-203a-5p
;
hsa-let-7b-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/609115; hsa-let-7i/Downstream/43498;
Nearest TSS
ENST00000382841/Upstream/3290;
ENST00000326765/Downstream/2860;
Nearest CpG islands
None/Target,
chr12-CpG: 104/Upstream/2837
,
chr12-CpG: 217/Downstream/2545
Nearest cancer related gene
CDKN1B
(TSG, No orient, 0)
Upstream sequence
CCTTGTTTATCAGATACATCACTGCTTGATGAAGCAAGGAAGATATACATGAAAATTTTAAAAATACATATCGCTGACTTCATGGAATGGACATCCTGTA
Downstream sequence
TAGCATTATGCAATTAGGTTTTTCCTTATTTGCTTCATTGTACTACCTGTGTATATAGTTTTTACCTTTTATGTAGCACATAAACTTTGGGGAAGGGAGG
Target sequence
TAAGCACTGAAAAACAACAACACAATAACACTAAAATTTTAGGCACTCTTAAATGATCTGCCTCTAAAAGCGTTGGATG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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